The ability of certain drugs to dissolve better in the body can make them more effective. Challenging drug compounds, which are poorly soluble, can be turned into a real winner if solubilization difficulties can be overcome.

NOVA-PhytoActif is a proprietary formulation technology designed to increase the solubility and enhance the bioavailability of plant-derived active chemical compounds that are poorly soluble.

In NOVA-PhytoActif proprietary formulation technology, the liquid extract is incorporated onto a carrier molecule by spray drying to form a stable mixture with enhanced solubility.

The process is depicted below:

Application of NOVA-PhytoActif Formulation Technology

NOVA-PhytoActif Formulation Technology is used to enhance the solubility of the following products: PhytoActif-Andrographis paniculata standardized extract
PhytoActif-Eclipta alba standardized extract

Andrographilide, which is one of the active ingredient of Andrographis paniculata standardized extract, has very poor water solubility and is poorly absorbed when taken orally. To enhance its oral absorption, NOVA-PhytoActif Formulation Technology is developed to produce an improved formulation.

The solubility of Andrographilide in our product PhytoActif-Andrographis paniculata standardized extract is 400% higher than the normal extract. (Refer to diagram below).